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What is potassium Oleate?
Potassium Cis-9-Octadecenoate. The chemical formula of potassium oleate (C18H33KO2) is C18H33KO2. Potassium is available as a brown liquid or solid. It is potassium fatty acids found in natural soaps. This potassium catalyst is mostly used to catalyze the reaction of polyisohydrourethane with polyurethane. This potassium catalyst can be used as a detergent, emulsifier or a bactericide. It can be used to kill any type of bacteria, including MRSA.
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OSHA 29 CFR 1910.1200 CLASSIFIES IT AS A HAZARDOUS SUBSTANCES. Eyes, respiratory system, and skin irritant. Ingestion of this material by accident can cause serious health problems. Acute poisoning by potassium after swallowing occurs rarely because vomiting often occurs and renal excretion happens quickly.
Potassium Oleate can be used “safely in the food or in the manufacturing of food components”, as long as the FDA is satisfied that it will act as a “binder” and “emulsifier”. Potassium Oleate may also be used to clean household products.
What uses does potassium oleate have?
Potassium isocyanurate (PUR) foam system uses potassium oleate as a trimerization and potassium catalyst. It is used widely in the polyurethane PIR foam board system. Additionally, potassium oleate has a wide range of uses, including rubber emulsifiers and foaming agents. Potassium Oleate acts as an emulsifier for many liquid soaps. It is also used in facial cleansers and mustache waxes. Emulsifiers are similar to surfactants in that they reduce the surface of liquids. Potassium Oleate helps to prevent the separation of ingredients into different chemicals.
Is potassium Oleate Natural?
Potassium Oleate occurs naturally in oils, such as sunflower. It is used as a soapmaking ingredient to create soaps with vegetable glycerin. In its purest form it can be irritating, but when used in soapmaking, it is reduced to a safe level and is approved for use as a food ingredient.
The different qualities of potassium-oleate products are: potassium-oleate solution, (potassium content less than 30%), is a colorless or light yellow viscous fluid, pasty potassium-oleate, (potassium content 50%), is a yellowish to light brown viscous liquid. Paste potassium-oleate, (potassium content 70%-92%), is a soft yellow paste solid, and potassium oleate powder (potassium content higher than 95%) is light yellow.
The potassium salts of fatty acid are made by adding potassium chloride to animal fats and plant oils. To make this active ingredient, fatty acids are obtained from palm, coconut oil, castor and cottonseed.
What are the true effects of potassium Oleate?
1. Through exothermic interactions, potassium oleate from natural soap components inactivates influenza virus of humans and birds.
Each year, influenza viruses spread, disrupting social activities at work and in schools. Medical expenses also increase. Influenza, it is believed, is the leading cause of death in the United States. It is also estimated that influenza is a major killer, especially among the elderly, people with chronic illnesses, and children. A pandemic can also be caused by new strains. People are still thinking about the outbreak and emergence of pandemic 2009 (H1N1), and they’re increasingly concerned that an epidemic of avian flu virus H5N1 subtype or H7N9 could occur in the future.
Influenza virus can be prevented with vaccines, and treated by anti-flu drugs. These measures may be ineffective due to antigenic mutations or drug resistance. In order to combat influenza virus infection, preventive measures are crucial. These include washing hands, wearing a face mask and using hand sanitizer.
Even though vaccines and antiviral drugs have been developed, an influenza epidemic still occurs. The prevention of influenza virus infections is crucial. This includes handwashing.
As a basic ingredient, hand soaps are made up of surfactants. In hand soaps, synthetic surfactants like sodium lauryl sulfate or sodium lauryl sulfate are used. Surfactants contribute to the detergency of soap and its foaming. It is made of fatty acids and natural oils. Soap can be used for hand soap. Surfactants are known to dissolve the bilayer membrane of the influenza virus particle, but the exact mechanism behind this is not clear.
The anti-influenza effects of the surfactants that are used in hand soaps: sodium Laureth sulfate(LES), sodium lauryl sulfate(SDS). C18.1 reduced infectivity for a strain of human influenza virus (H3N2) to 4 logs or higher, while LES and SDS decreased infectivity to 1 log or lower. A strain of avian influenza (H5N3) produced similar results. By using isothermal calorimetry, the interaction between virus and surfactant was investigated. The LES-virus showed a value of enthalpy (DH) that was positive, indicating an interaction with a hydrophobic nature. Both the C18-1-virus and SDS-virus systems showed negative values of DH. These indicate an endothermic reaction that indicates an electrical reaction. The DH value for the C18:1 virus system was significantly higher than that for the SDS virus system. A mixture of C18 and HA protein also showed negative values for DH.
These results indicate influenza virus inactivation through hydrophobic interaction between a surfactant and the viral envelope, is not sufficient to prevent infection. Inactivation via electrical interaction between a surfactant and HA proteins can prevent influenza virus infection.
Wounds are often infected with bacteria. Potassium C18:1K, a type potassium fatty acids, reduced the number of Staphylococcus Aureus and Escherichia Coli by >4 logs within 10 minutes. Clostridium Difficult was reduced by >2 logs within one minute. C181K (proportion of biofilms removed: 90.3%), was significantly more efficient at removing Staphylococcus spp. biofilms compared to the synthetic surfactant soaps sodium laurylethersulfate(SLES) (74.8%) and sodium sulfate(SLS)78.0% (p 0.01);
In the water-soluble tetrazolium (WST) assay, BALB/3T3 cloneA31 mouse fibroblasts in C18-1K (relative survival vs. controls: 102.8%) showed a significantly higher level of viability than mice in SLES (30.1%), SLS (18.1%), p 0.05 C181K (relative leaked compared to control: 1089%) was associated with a lower LDH from mouse fibroblasts compared to SLES and SLS (702.6% and 523.4%), respectively (p 0.05). Potassium-oleate exhibited bactericidal properties against various species such as Staphylococcus aureus and Escherichia coelia, Bacillus cereus and Clostridium difficile.
It is essential to disinfect and remove bacteria that cause infection, including Staphylococcus or MRSA and their resistant forms, as well as biofilm-forming MRSA. This will help prevent infections and improve wound care. We investigated whether natural soaps that are free of additives, preservatives and synthetic materials could be used to achieve this goal. In order to determine the effectiveness of different types of fatty-acid potassium in removing MRSA, we investigated their cytotoxicity and bactericidal properties.
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